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What is goose deoxycholic acid and what are its effects?

click:date:2024/1/20

Goose deoxycholic acid, also known as 3 α, seven α- Dihydroxy-5 β- Bile-24-carboxylic acid is a white crystalline substance that is insoluble in water but soluble in ethanol and acetic acid. Its melting point is between 165-167 ° C. Goose deoxycholic acid and bile acid are the two main components of bile produced by the liver. The main function is to reduce the saturation of cholesterol in the bile. After taking CDCA, the lipids in the majority of patients return to a micro colloidal state, and cholesterol is in an unsaturated state, thereby dissolving and shedding cholesterol in the stones. This product is currently one of the largest drugs used to treat gallstones in the world, and it is also a raw material for synthesizing ursodeoxycholic acid (UDCA) and other steroid compounds.




Product name: Goose deoxycholic acid
HPLC content determination: ≥ 95.0%
Quality standards: Internal control standards
CAS number: 474-25-9
Chemical name: 3 α , seven α – Dihydroxy-5 β- Bile-24-acid
Molecular formula: C24H40O4
Molecular weight: 392.58 g/mol
Appearance: White or almost white powder.
Solubility: Easily soluble in ethanol, almost insoluble in water.
Specific rotation:+11.0 ° to+13.0 ° (2% ethanol solution)
Drying weight loss: not more than 2.0% (dried to constant weight at 105 ° C)
Burning residue: not more than 0.1%
Heavy metals: not exceeding 20 ppm
Chloride: not more than 0.1%
Translucency: not less than 40.0%
Gallic acid: not more than 0.1%
Cholic acid: not more than 1.0%
Other individual impurities: not more than 1.0%
Total impurities: not more than 5.0%
Usage: Used for cholesterol gallstones, it also has certain therapeutic effects on pigment gallstones and mixed gallstones.


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